Performance of a dose calibrator for radioactivity measurements of 99mTc-generator manufactured at Malaysian Nuclear Agency

N Jamal; A R Rahimah; F S M Chaculi; Z Ibrahim; R Dahalan

N Jamal
A R Rahimah
F S M Chaculi
Z Ibrahim
R Dahalan

Keywords: 99mTc Generator, dose calibrator and radioactivity measurement

Abstract

ABSTRACT

We sought to test the performance of a dose calibrator for radioactivity measurements of ^99mTc generator manufactured at the Malaysian Nuclear Agency. Parameters tested are accuracy, constancy and linearity. Result of accuracy test using ¹³⁷Cs, ⁶⁰Co and ⁵⁷Co reference sources were (-2.80%) and (2.62 to 2.72%) respectively. While result of constancy test using ¹³⁷Cs and ^99mTc were (0.002 to 0.023%) and (-0.008 to -0.01%) respectively. The result of linearity test using ^99mTc shows the diference of less than 10% between the measured and calculated radioactivity. The plot shows an excellent linearity between 19 mCi to 305 mCi. It indicates that the dose calibrator for radioactivity measurements of ^99mTc generator manufactured at the Malaysian Nuclear Agency was giving the actual prescribed radioactivity. This may ensure traceability of measurements of the radioactivity of ^99mTc used in nuclear medicine practice.

ABSTRAK

Prestasi alat tentukuran dos untuk pengukuran radioaktiviti penjana ^99mTc yang dihasilkan di Agensi Nuklear Malaysia telah diuji. Parameter yang diuji adalah ketepatan, ketetapan/kemalaran dan kelinearan. Keputusan ujian ketepatan menggunakan ¹³⁷Cs, ⁶⁰Co dan punca rujukan ⁵⁷Co adalah (-2.80%) dan (2.62 hingga 2.72%). Keputusan ujian ketetapan/kemalaran menggunakan ¹³⁷Cs dan ^99mTc adalah (0.002 hingga 0.023%) dan (-0.008 hingga 0.01%). Keputusan ujian kelinearan menggunakan ^99mTc menunjukkan perbezaan yang tidak melebihi 10% di antara radioaktiviti yang diukur dan yang dikira. Plot menunjukkan kelinearan yang sangat baik antara 19 mCi hingga 305 mCi. Ini menunjukkan bahawa alat tentukuran dos untuk ukuran radioaktiviti penjana ^99mTc yang dihasilkan di Agensi Nuklear Malaysia memberikan radioaktiviti sebenar. Maklumat yang diperolehi telah memberi kepastian kebolehkesanan pengukuran radioaktiviti ^99mTc digunakan dalam amalan perubatan nuklear.